troxacitabine

{
  "id": "MLC-T-ONC-008926",
  "term": "troxacitabine",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug being studied for use as an anticancer agent.",
    "A dioxolane derivative and a novel L-configuration deoxycytidine analogue with potent antineoplastic activity. When incorporated into growing chain during DNA replication, troxacitabine stops DNA polymerization due to its unnatural L-configuration, in contrast to the normal nucleotides with D-configuration. As a result, this agent terminates DNA synthesis upon incorporated into DNA molecules, and consequently interrupts tumor cell proliferation."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/troxacitabine/"
}