tusamitamab ravtansine

{
  "id": "MLC-T-ONC-017371",
  "term": "tusamitamab ravtansine",
  "field": "Oncology and biomedicine",
  "definition": "An immunoconjugate consisting of anti-carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) conjugated to a cytotoxic agent, with potential antineoplastic activity. Upon administration of tusamitamab ravtansine the antibody moiety targets CEACAM5 on tumor cells. Upon antibody/antigen binding and internalization, the immunoconjugate releases the cytotoxic agent, which results in tumor cell death. CEACAM5, a member of the CEA family of proteins that plays a key role in cell migration, cell invasion, and cell adhesion, is overexpressed by a variety of cancer cell types.",
  "synonyms": [
    "ADC SAR408701",
    "anti-CEACAM5 antibody-drug conjugate SAR408701"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tusamitamab-ravtansine/"
}