Actinomycin D

{
  "id": "MLC-T-AGR-000072",
  "term": "Actinomycin D",
  "field": "Agriculture and food",
  "definition": "A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from Streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy.",
  "synonyms": [
    "dactinomycin"
  ],
  "subject": "Research, Technology, Methods",
  "see_also": [
    "peptide antibiotics",
    "cyclic peptides",
    "antineoplastic agents",
    "heterocyclic compounds"
  ],
  "references": [
    "Medical Subject Headings 2011",
    "NAL Agricultural Thesaurus and Glossary"
  ],
  "translations": {
    "es": "actinomicina D"
  },
  "url": "https://mlchart.com/terminology/agriculture/actinomycin-d/"
}