Physiologically based pharmacokinetic modeling

{
  "id": "MLC-T-CHM-008955",
  "term": "Physiologically based pharmacokinetic modeling",
  "field": "Chemistry",
  "definition": "A mathematical modeling approach that uses physiological and biochemical parameters to predict the absorption, distribution, metabolism, and excretion (ADME) of chemicals in biological systems. This method integrates organ volumes, blood flows, and tissue-specific enzyme activities to simulate chemical disposition. It provides a mechanistic understanding of chemical behavior within the body.",
  "synonyms": [
    "toxicologically based pharmacokinetic modeling"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1583. 'Explanatory dictionary of key terms in toxicology (IUPAC Recommendations 2007)' on page 1607 (https://doi.org/10.1351/pac200779091583)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/physiologically-based-pharmacokinetic-modeling/"
}