Single nucleotide polymorphism

{
  "id": "MLC-T-ENV-025634",
  "term": "Single nucleotide polymorphism",
  "field": "Environment",
  "term_source": "Single Nucleotide Polymorphism",
  "definition": "1. A change in which a single base in the DNA differs from the usual base at that position.\n\n2. A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.\n\n3. A variant DNA sequence in which the purine or pyrimidine base (as cytosine) of a single nucleotide has been replaced by another such base (as thymine).\n\n4. Single nucleotide polymorphisms (SNPs) are a type of polymorphism involving variation of a single base pair.\n\n5. A SNP (pronounced \"snip\") is a small genetic change, or variation, that can occur within an organism's DNA sequence. The genetic code is specified by the four nucleotides: adenine, cytosine, thymine, and guanine. SNP variation occurs when a single nucleotide, such as adenine, replaces one of the other three nucleotides. SNPs found within a coding sequence are of particular interest to researchers because they are more likely to alter the biological function of a protein. Because of the recent advances in technology, coupled with the unique ability of these genetic variations to facilitate gene identification, there has been a heightened activities of SNP discovery and detection.",
  "abbreviation": "SNP",
  "subject": "Biological substances",
  "references": [
    "EPA Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA (Glossary): EPA Science Policy Council at http://www.epa.gov/osa/pdfs/EPA-Genomics-White-Paper.pdf at http://www.epa.gov/osa/pdfs/EPA-Genomics-White-Paper.pdf",
    "NIH Genetics Home Reference Glossary",
    "NOAA Coral Reef Glossary"
  ],
  "url": "https://mlchart.com/terminology/environment/single-nucleotide-polymorphism/"
}