Single nucleotide polymorphism

{
  "id": "MLC-T-CHM-010891",
  "term": "Single nucleotide polymorphism",
  "field": "Chemistry",
  "definition": "A variation in a single nucleotide base pair at a specific position in the deoxyribonucleic acid (DNA) sequence among individuals or paired chromosomes. These genetic markers are the most common type of genetic variation and can influence an organism's susceptibility to disease or its response to drugs. They are widely used in genetic mapping, pharmacogenomics, and forensic analysis.",
  "synonyms": [
    "point mutation"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "nucleotide sequence",
    "purine",
    "pyrimidine"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1153 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/single-nucleotide-polymorphism/"
}