Human leukocyte antigen polymorphism

{
  "id": "MLC-T-CHM-005423",
  "term": "Human leukocyte antigen polymorphism",
  "field": "Chemistry",
  "definition": "The existence of multiple alleles for human leukocyte antigen (HLA) genes within the human population, leading to a wide array of HLA protein combinations on individual cells. This genetic variation results in each person having a unique set of HLA molecules, which influences susceptibility to autoimmune diseases and transplant compatibility. The high degree of polymorphism is a key factor in immune system function.",
  "synonyms": [
    "HLA Polymorphism"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "major histocompatibility complex",
    "rheumatoid arthritis"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1178 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/human-leukocyte-antigen-polymorphism/"
}