Leukocyte functional antigen

Term · Chemistry · MLC-T-CHM-006534

Any of a group of leukocyte surface adhesion molecules, designated LFA-1, LFA-2, and LFA-3, that mediate intercellular adhesion in immune responses such as T cell killing and contact between lymphocytes and antigen-presenting cells. LFA-1 is an integrin that binds the intercellular adhesion molecules ICAM-1, ICAM-2, and ICAM-3, whereas LFA-2 (CD2) and LFA-3 (CD58) are immunoglobulin superfamily members that bind each other.

Table 1. Record
Identifier	MLC-T-CHM-006534
Field	Chemistry
Subject	Chemistry and Human Health
References	PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1201 (https://doi.org/10.1351/PAC-REC-11-06-03)

Record as JSON

{
  "id": "MLC-T-CHM-006534",
  "term": "Leukocyte functional antigen",
  "field": "Chemistry",
  "definition": "Any of a group of leukocyte surface adhesion molecules, designated LFA-1, LFA-2, and LFA-3, that mediate intercellular adhesion in immune responses such as T cell killing and contact between lymphocytes and antigen-presenting cells. LFA-1 is an integrin that binds the intercellular adhesion molecules ICAM-1, ICAM-2, and ICAM-3, whereas LFA-2 (CD2) and LFA-3 (CD58) are immunoglobulin superfamily members that bind each other.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1201 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/leukocyte-functional-antigen/"
}

Record 6,926 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.