Leukocyte common antigen

{
  "id": "MLC-T-CHM-006533",
  "term": "Leukocyte common antigen",
  "field": "Chemistry",
  "definition": "A transmembrane glycoprotein expressed on the surface of most hematopoietic cells, excluding mature erythrocytes and platelets. This antigen, also known as CD45, is a protein tyrosine phosphatase that regulates signal transduction in immune cells. Its isoforms vary depending on the cell type and activation state of the leukocyte.",
  "synonyms": [
    "CD45"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1201 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/leukocyte-common-antigen/"
}