Human leukocyte antigen type II

{
  "id": "MLC-T-CHM-005425",
  "term": "Human leukocyte antigen type II",
  "field": "Chemistry",
  "definition": "A class of human leukocyte antigen (HLA) molecules primarily expressed on antigen-presenting cells such as B lymphocytes, macrophages, and dendritic cells. These proteins present extracellular antigens to CD4+ T-helper cells, initiating an adaptive immune response. They are encoded by genes within the HLA-D region of the major histocompatibility complex.",
  "synonyms": [
    "HLA Type II"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "CD4",
    "T-cell receptor",
    "antigen-presenting cell",
    "dendritic cell",
    "lymphocyte",
    "macrophage",
    "non-self",
    "peptide-binding groove"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1178 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/human-leukocyte-antigen-type-ii/"
}