MLchartDataset catalogue

Ia antigen

Term · Chemistry · MLC-T-CHM-005560

A class II major histocompatibility complex (MHC) protein found on the surface of antigen-presenting cells, such as B lymphocytes, macrophages, and dendritic cells. These molecules are responsible for presenting processed foreign antigens to T helper cells, initiating an immune response. Ia antigens are encoded by genes within the MHC region.

Table 1. Record
IdentifierMLC-T-CHM-005560
FieldChemistry
SubjectChemistry and Human Health
SynonymsI region-associated antigen; immune response-associated antigen
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1181 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoB lymphocyte; Alloantigen; Immune response-associated protein; Macrophage; H-2 complex; Major histocompatibility complex class II molecule; Serology
Record as JSON
{
  "id": "MLC-T-CHM-005560",
  "term": "Ia antigen",
  "field": "Chemistry",
  "definition": "A class II major histocompatibility complex (MHC) protein found on the surface of antigen-presenting cells, such as B lymphocytes, macrophages, and dendritic cells. These molecules are responsible for presenting processed foreign antigens to T helper cells, initiating an immune response. Ia antigens are encoded by genes within the MHC region.",
  "synonyms": [
    "I region-associated antigen",
    "immune response-associated antigen"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "alloantigen",
    "immune response-associated protein",
    "macrophage",
    "H-2 complex",
    "major histocompatibility complex class II molecule",
    "serology"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1181 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/ia-antigen/"
}

Record 5,900 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.