Antigen processing
Term · Chemistry · MLC-T-CHM-000681
The intracellular biochemical pathways by which protein antigens are degraded into smaller peptide fragments suitable for binding to major histocompatibility complex (MHC) molecules. These peptide-MHC complexes are then transported to the cell surface for presentation to T lymphocytes. This process occurs in both the cytoplasm for MHC class I and in endosomal compartments for MHC class II.
| Identifier | MLC-T-CHM-000681 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1125 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | Major histocompatibility complex class I molecule; T lymphocyte; Antigen presentation; Antigen receptor; Antigen-presenting cell; Major histocompatibility complex class II molecule |
Record as JSON
{
"id": "MLC-T-CHM-000681",
"term": "Antigen processing",
"field": "Chemistry",
"definition": "The intracellular biochemical pathways by which protein antigens are degraded into smaller peptide fragments suitable for binding to major histocompatibility complex (MHC) molecules. These peptide-MHC complexes are then transported to the cell surface for presentation to T lymphocytes. This process occurs in both the cytoplasm for MHC class I and in endosomal compartments for MHC class II.",
"subject": "Chemistry and Human Health",
"see_also": [
"major histocompatibility complex class I molecule",
"T lymphocyte",
"antigen presentation",
"antigen receptor",
"antigen-presenting cell",
"major histocompatibility complex class II molecule"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1125 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/antigen-processing/"
}
Record 726 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.