Major histocompatibility complex class I molecule

{
  "id": "MLC-T-CHM-006929",
  "term": "Major histocompatibility complex class I molecule",
  "field": "Chemistry",
  "definition": "A cell surface glycoprotein found on nearly all nucleated cells, responsible for presenting intracellular antigens to cytotoxic T lymphocytes. These molecules display peptides derived from proteins synthesized within the cell, including viral proteins or tumor antigens. They consist of an alpha chain non-covalently associated with beta-2 microglobulin.",
  "synonyms": [
    "class I MHC gene product",
    "MHC class I molecule"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "antigen presentation",
    "major histocompatibility complex"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/major-histocompatibility-complex-class-i-molecule/"
}