MLchartDataset catalogue

Major histocompatibility complex molecule

Term · Chemistry · MLC-T-CHM-006932

A cell surface glycoprotein encoded by the major histocompatibility complex gene family, responsible for presenting processed antigens to T cells. These molecules are highly polymorphic, creating a wide diversity of antigen-presenting capabilities within a population. The recognition of these molecules as foreign (alloantigens) is the primary cause of transplant rejection between genetically different individuals.

Table 1. Record
IdentifierMLC-T-CHM-006932
FieldChemistry
SubjectChemistry and Human Health
SynonymsMHC molecule
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoAlloantigen; Major histocompatibility complex; Rejection
Record as JSON
{
  "id": "MLC-T-CHM-006932",
  "term": "Major histocompatibility complex molecule",
  "field": "Chemistry",
  "definition": "A cell surface glycoprotein encoded by the major histocompatibility complex gene family, responsible for presenting processed antigens to T cells. These molecules are highly polymorphic, creating a wide diversity of antigen-presenting capabilities within a population. The recognition of these molecules as foreign (alloantigens) is the primary cause of transplant rejection between genetically different individuals.",
  "synonyms": [
    "MHC molecule"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "alloantigen",
    "major histocompatibility complex",
    "rejection"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/major-histocompatibility-complex-molecule/"
}

Record 7,343 of 13,678 in Chemistry terminology (MLC-0109). Request the full dataset.