Major histocompatibility complex

{
  "id": "MLC-T-CHM-006928",
  "term": "Major histocompatibility complex",
  "field": "Chemistry",
  "definition": "A set of genes encoding cell surface glycoproteins that bind peptide antigens and present them to T lymphocytes. This presentation allows the immune system to recognize and respond to foreign pathogens or abnormal cells. In humans, the major histocompatibility complex is known as the Human Leukocyte Antigen (HLA) system, located on chromosome 6.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "H-2",
    "H-2 complex",
    "major histocompatibility complex class II molecule",
    "major histocompatibility complex class I molecule",
    "T lymphocyte",
    "antigen presentation",
    "graft rejection",
    "human leukocyte antigen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1208 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/major-histocompatibility-complex/"
}