Antigen presentation

{
  "id": "MLC-T-CHM-000680",
  "term": "Antigen presentation",
  "field": "Chemistry",
  "definition": "The process by which certain immune cells, known as antigen-presenting cells (APCs), display fragments of antigens on their surface for recognition by T lymphocytes. The antigen fragments, or peptides, are bound to major histocompatibility complex (MHC) molecules. Class I MHC molecules present endogenous antigens to cytotoxic T cells, while Class II MHC molecules present exogenous antigens to helper T cells, initiating an adaptive immune response.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "major histocompatibility complex molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1125 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/antigen-presentation/"
}