Human leukocyte antigen type I

{
  "id": "MLC-T-CHM-005424",
  "term": "Human leukocyte antigen type I",
  "field": "Chemistry",
  "definition": "A class of major histocompatibility complex (MHC) proteins expressed on the surface of nearly all nucleated cells. These proteins present endogenous antigens, such as viral peptides or tumor antigens, to cytotoxic T lymphocytes (CD8+ T cells). This interaction triggers the destruction of infected or abnormal cells.",
  "synonyms": [
    "HLA Type I"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CD8+ T suppressor cell",
    "T-cell receptor",
    "cytotoxic T lymphocyte",
    "lymphocyte",
    "peptide-binding groove"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1178 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/human-leukocyte-antigen-type-i/"
}