CD8

{
  "id": "MLC-T-CHM-001769",
  "term": "CD8",
  "field": "Chemistry",
  "definition": "A transmembrane glycoprotein that functions as a co-receptor on the surface of cytotoxic T lymphocytes. It binds to the major histocompatibility complex (MHC) class I molecule on antigen-presenting cells, stabilizing the interaction with the T-cell receptor. This binding event is a necessary step for the activation of the cytotoxic T cell to eliminate infected or malignant cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "cytotoxic T lymphocyte",
    "major histocompatibility complex class I molecule",
    "superfamily"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1138 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cd8/"
}