Coreceptor

{
  "id": "MLC-T-CHM-002581",
  "term": "Coreceptor",
  "field": "Chemistry",
  "definition": "A cell-surface protein that binds to a ligand concurrently with a primary receptor to initiate or modulate a cellular signal. The coreceptor itself may not bind the primary ligand but stabilizes the receptor-ligand interaction and participates in the signaling cascade. In T-cell activation, CD4 and CD8 are coreceptors that bind to the major histocompatibility complex (MHC) molecule alongside the T-cell receptor's binding to the antigenic peptide.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B-cell receptor",
    "CD4",
    "CD8",
    "T lymphocyte",
    "T-cell receptor",
    "major histocompatibility complex molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1150 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/coreceptor/"
}