Tumor rejection antigen

{
  "id": "MLC-T-CHM-012352",
  "term": "Tumor rejection antigen",
  "field": "Chemistry",
  "definition": "A molecule expressed on the surface of tumor cells that can be recognized by the host's immune system, leading to the destruction of the tumor. These antigens are presented by major histocompatibility complex (MHC) molecules and are targeted by cytotoxic T lymphocytes. Tumor rejection antigens are classified into several groups, including tumor-specific antigens that arise from mutations unique to the cancer cell and tumor-associated antigens which are also expressed on some normal cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "antibody therapy",
    "immune system"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1256 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tumor-rejection-antigen/"
}