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Tumor-specific transplantation antigen

Term · Chemistry · MLC-T-CHM-012355

An antigen expressed exclusively by tumor cells and not by normal cells, capable of eliciting an immune response that leads to the rejection of the tumor in a transplanted setting. These antigens are highly specific to the tumor and are ideal targets for cancer immunotherapy. They are often products of oncogenic mutations.

Table 1. Record
IdentifierMLC-T-CHM-012355
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1256 (https://doi.org/10.1351/PAC-REC-11-06-03)
Record as JSON
{
  "id": "MLC-T-CHM-012355",
  "term": "Tumor-specific transplantation antigen",
  "field": "Chemistry",
  "definition": "An antigen expressed exclusively by tumor cells and not by normal cells, capable of eliciting an immune response that leads to the rejection of the tumor in a transplanted setting. These antigens are highly specific to the tumor and are ideal targets for cancer immunotherapy. They are often products of oncogenic mutations.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1256 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tumor-specific-transplantation-antigen/"
}

Record 13,172 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.