Minor histocompatibility antigen

{
  "id": "MLC-T-CHM-007406",
  "term": "Minor histocompatibility antigen",
  "field": "Chemistry",
  "definition": "Peptides derived from polymorphic cellular proteins that, when presented by major histocompatibility complex (MHC) molecules, can elicit a T-cell immune response. These antigens are less potent than MHC antigens in triggering graft rejection but can still cause chronic rejection. They are particularly relevant in allogeneic transplantation, where donor and recipient are MHC-matched.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "graft rejection",
    "major histocompatibility complex"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1213 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/minor-histocompatibility-antigen/"
}