MLchartDataset catalogue

Mixed lymphocyte response

Term · Chemistry · MLC-T-CHM-007427

An in vitro immunological assay used to assess the histocompatibility between two individuals, typically by co-culturing lymphocytes from both. When T lymphocytes from one individual recognize foreign major histocompatibility complex (MHC) antigens on the cells of another, they proliferate. This response is a measure of the potential for graft rejection in transplantation.

Table 1. Record
IdentifierMLC-T-CHM-007427
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1213 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoT lymphocyte; Allogeneic; Major histocompatibility complex molecule
Record as JSON
{
  "id": "MLC-T-CHM-007427",
  "term": "Mixed lymphocyte response",
  "field": "Chemistry",
  "definition": "An in vitro immunological assay used to assess the histocompatibility between two individuals, typically by co-culturing lymphocytes from both. When T lymphocytes from one individual recognize foreign major histocompatibility complex (MHC) antigens on the cells of another, they proliferate. This response is a measure of the potential for graft rejection in transplantation.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "allogeneic",
    "major histocompatibility complex molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1213 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/mixed-lymphocyte-response/"
}

Record 7,878 of 13,678 in Chemistry terminology (MLC-0109). Request the full dataset.