Lymphocyte transformation test

{
  "id": "MLC-T-CHM-006835",
  "term": "Lymphocyte transformation test",
  "field": "Chemistry",
  "definition": "An in vitro assay used to assess lymphocyte proliferation and activation in response to mitogens or specific antigens. Lymphocytes are cultured with stimulating agents, and their subsequent DNA synthesis, often measured by the incorporation of tritiated thymidine, indicates the degree of cellular activation. This test provides insight into the functional capacity of a patient's cellular immune response.",
  "synonyms": [
    "blastogenesis assay",
    "lymphocyte blastogenesis assay (LBA)"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "lymphocyte proliferation test",
    "lymphocyte",
    "mitogen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1205 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lymphocyte-transformation-test/"
}