Memory lymphocyte immunostimulation assay
Term · Chemistry · MLC-T-CHM-007171
A blood test, a refined form of the lymphocyte transformation test, in which a patient's lymphocytes are cultured with a suspected allergen such as nickel and the proliferation of allergen-specific memory T cells is measured, classically by tritiated thymidine uptake. It serves to detect delayed type IV hypersensitivity to metals and other chemicals. Reactivity is reported as a stimulation index, the ratio of proliferation with allergen to proliferation without it.
| Identifier | MLC-T-CHM-007171 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1212 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | Enzyme-linked immunosorbent assay; Lymphocyte transformation test |
Record as JSON
{
"id": "MLC-T-CHM-007171",
"term": "Memory lymphocyte immunostimulation assay",
"field": "Chemistry",
"definition": "A blood test, a refined form of the lymphocyte transformation test, in which a patient's lymphocytes are cultured with a suspected allergen such as nickel and the proliferation of allergen-specific memory T cells is measured, classically by tritiated thymidine uptake. It serves to detect delayed type IV hypersensitivity to metals and other chemicals. Reactivity is reported as a stimulation index, the ratio of proliferation with allergen to proliferation without it.",
"subject": "Chemistry and Human Health",
"see_also": [
"enzyme-linked immunosorbent assay",
"lymphocyte transformation test"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1212 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/memory-lymphocyte-immunostimulation-assay/"
}
Record 7,598 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.