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Memory lymphocyte immunostimulation assay

Term · Chemistry · MLC-T-CHM-007171

A blood test, a refined form of the lymphocyte transformation test, in which a patient's lymphocytes are cultured with a suspected allergen such as nickel and the proliferation of allergen-specific memory T cells is measured, classically by tritiated thymidine uptake. It serves to detect delayed type IV hypersensitivity to metals and other chemicals. Reactivity is reported as a stimulation index, the ratio of proliferation with allergen to proliferation without it.

Table 1. Record
IdentifierMLC-T-CHM-007171
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1212 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoEnzyme-linked immunosorbent assay; Lymphocyte transformation test
Record as JSON
{
  "id": "MLC-T-CHM-007171",
  "term": "Memory lymphocyte immunostimulation assay",
  "field": "Chemistry",
  "definition": "A blood test, a refined form of the lymphocyte transformation test, in which a patient's lymphocytes are cultured with a suspected allergen such as nickel and the proliferation of allergen-specific memory T cells is measured, classically by tritiated thymidine uptake. It serves to detect delayed type IV hypersensitivity to metals and other chemicals. Reactivity is reported as a stimulation index, the ratio of proliferation with allergen to proliferation without it.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "enzyme-linked immunosorbent assay",
    "lymphocyte transformation test"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1212 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/memory-lymphocyte-immunostimulation-assay/"
}

Record 7,598 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.