Lymphocyte-activating factor

{
  "id": "MLC-T-CHM-006836",
  "term": "Lymphocyte-activating factor",
  "field": "Chemistry",
  "definition": "An obsolete name for a cytokine, produced primarily by activated macrophages, that stimulates the proliferation and differentiation of T lymphocytes. This factor was later identified as a specific protein and is now known as interleukin-1 (IL-1). The term reflects its originally observed biological activity before its molecular structure and identity within the broader interleukin family were determined.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "interleukin"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1204 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lymphocyte-activating-factor/"
}