Transforming growth factor β

{
  "id": "MLC-T-CHM-012219",
  "term": "Transforming growth factor β",
  "field": "Chemistry",
  "definition": "A multifunctional cytokine that controls proliferation, cellular differentiation, and other functions in most cells. It is a secreted protein that exists in at least three isoforms: TGF-β1, TGF-β2, and TGF-β3. This protein has a potent immunosuppressive effect on lymphocytes and macrophages, and it also participates in wound healing and tissue fibrosis.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "immune system",
    "lymphocyte",
    "macrophage",
    "superfamily"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1255 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/transforming-growth-factor-b/"
}