Tumor necrosis factor

{
  "id": "MLC-T-CHM-012349",
  "term": "Tumor necrosis factor",
  "field": "Chemistry",
  "definition": "A type of cytokine, a signaling protein, primarily produced by macrophages and other immune cells in response to infection and inflammation. It plays a central part in the inflammatory response, can induce fever, and has the ability to cause apoptosis (cell death) in certain types of tumor cells. The two main forms are TNF-alpha and TNF-beta (lymphotoxin-alpha).",
  "synonyms": [
    "cachectin",
    "cachexin",
    "TNF-α"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "cytokine",
    "leukocyte",
    "systemic"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1256 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tumor-necrosis-factor/"
}