Lymphotoxin
Term · Chemistry · MLC-T-CHM-006848
A cytokine, also known as tumor necrosis factor-beta (TNF-β), produced and secreted by activated lymphocytes, particularly T cells. It acts as a mediator of inflammatory and immune responses by binding to specific cell surface receptors and initiating a signaling cascade within the target cell. Lymphotoxin is involved in the development of lymphoid organs and can induce programmed cell death (apoptosis) in certain tumor cells and virus-infected cells.
| Identifier | MLC-T-CHM-006848 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| Synonyms | Tumor necrosis factor β (TNF-β). |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1207 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | T lymphocyte; Cytokine; Cytotoxic |
Record as JSON
{
"id": "MLC-T-CHM-006848",
"term": "Lymphotoxin",
"field": "Chemistry",
"definition": "A cytokine, also known as tumor necrosis factor-beta (TNF-β), produced and secreted by activated lymphocytes, particularly T cells. It acts as a mediator of inflammatory and immune responses by binding to specific cell surface receptors and initiating a signaling cascade within the target cell. Lymphotoxin is involved in the development of lymphoid organs and can induce programmed cell death (apoptosis) in certain tumor cells and virus-infected cells.",
"synonyms": [
"Tumor necrosis factor β (TNF-β)."
],
"subject": "Chemistry and Human Health",
"see_also": [
"T lymphocyte",
"cytokine",
"cytotoxic"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1207 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/lymphotoxin/"
}
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