Activation-induced cell death

{
  "id": "MLC-T-CHM-000180",
  "term": "Activation-induced cell death",
  "field": "Chemistry",
  "definition": "A form of programmed cell death, or apoptosis, that is triggered in mature lymphocytes following their repeated stimulation through their antigen receptors. This process is a homeostatic mechanism that controls the size of the lymphocyte population after an immune response has resolved, eliminating effector cells. The Fas/FasL signaling pathway is a primary molecular mechanism responsible for initiating this type of apoptosis.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "lymphocyte",
    "memory cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1116 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/activation-induced-cell-death/"
}