Fas

{
  "id": "MLC-T-CHM-004347",
  "term": "Fas",
  "field": "Chemistry",
  "definition": "A transmembrane protein that functions as a death receptor on the surface of cells, also designated as CD95 or APO-1. When this receptor is bound by its corresponding ligand (FasL), it triggers a signaling pathway that results in apoptosis, or programmed cell death. This process is a key part of immune system regulation, including the elimination of self-reactive lymphocytes and the killing of virus-infected or tumor cells by cytotoxic T cells.",
  "synonyms": [
    "CD95"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "cytotoxic",
    "target cell",
    "tumor necrosis factor"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1165 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/fas/"
}