Granzyme

{
  "id": "MLC-T-CHM-005002",
  "term": "Granzyme",
  "field": "Chemistry",
  "definition": "A family of serine proteases found in the granules of cytotoxic T lymphocytes and natural killer cells. These enzymes are released into target cells, such as virus-infected cells or tumor cells, where they induce apoptosis (programmed cell death). Granzymes, particularly granzyme B, act in conjunction with perforin to eliminate compromised cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "cytotoxic T lymphocyte",
    "natural killer cell",
    "perforin",
    "target cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1172 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/granzyme/"
}