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Natural killer cell activity assay

Term · Chemistry · MLC-T-CHM-007779

An in vitro method for measuring the cytotoxic capacity of natural killer (NK) cells, a component of the innate immune system. The assay quantifies the ability of NK cells isolated from a sample to lyse specific target cells, such as tumor cells or virus-infected cells. A common method is the chromium release assay, where the amount of radioactive chromium released from pre-labeled target cells corresponds to the level of cell death.

Table 1. Record
IdentifierMLC-T-CHM-007779
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1219 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoChromium release assay; Lymphoid tissue; Natural killer cell
Record as JSON
{
  "id": "MLC-T-CHM-007779",
  "term": "Natural killer cell activity assay",
  "field": "Chemistry",
  "definition": "An in vitro method for measuring the cytotoxic capacity of natural killer (NK) cells, a component of the innate immune system. The assay quantifies the ability of NK cells isolated from a sample to lyse specific target cells, such as tumor cells or virus-infected cells. A common method is the chromium release assay, where the amount of radioactive chromium released from pre-labeled target cells corresponds to the level of cell death.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "chromium release assay",
    "lymphoid tissue",
    "natural killer cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1219 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/natural-killer-cell-activity-assay/"
}

Record 8,260 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.