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Lymphokine-activated killer cell

Term · Chemistry · MLC-T-CHM-006844

A type of cytotoxic lymphocyte that exhibits enhanced tumor-killing activity after being stimulated with certain lymphokines, particularly interleukin-2. These cells are derived from natural killer cells or T lymphocytes and are capable of lysing a broad spectrum of tumor cells without prior sensitization. Their activity is often explored in adoptive immunotherapy for cancer treatment.

Table 1. Record
IdentifierMLC-T-CHM-006844
FieldChemistry
SubjectChemistry and Human Health
SynonymsLAK cell; lymphocyte-activated killer cell
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1206 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoKiller cell; Interleukin; Natural killer cell; Target cell
Record as JSON
{
  "id": "MLC-T-CHM-006844",
  "term": "Lymphokine-activated killer cell",
  "field": "Chemistry",
  "definition": "A type of cytotoxic lymphocyte that exhibits enhanced tumor-killing activity after being stimulated with certain lymphokines, particularly interleukin-2. These cells are derived from natural killer cells or T lymphocytes and are capable of lysing a broad spectrum of tumor cells without prior sensitization. Their activity is often explored in adoptive immunotherapy for cancer treatment.",
  "synonyms": [
    "LAK cell",
    "lymphocyte-activated killer cell"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "killer cell",
    "interleukin",
    "natural killer cell",
    "target cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1206 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lymphokine-activated-killer-cell/"
}

Record 7,248 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.