B-lymphocyte-induced maturation protein 1

{
  "id": "MLC-T-CHM-001400",
  "term": "B-lymphocyte-induced maturation protein 1",
  "field": "Chemistry",
  "definition": "A transcriptional repressor protein that drives the terminal differentiation of B lymphocytes into antibody-secreting plasma cells. This protein, also known as BLIMP-1, suppresses the expression of genes associated with B-cell identity and proliferation, while activating genes involved in antibody production and secretion. Its expression is tightly regulated during the germinal center reaction.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "affinity maturation",
    "class switching",
    "germinal center",
    "plasma cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1133 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/b-lymphocyte-induced-maturation-protein-1/"
}