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Ciliary neurotrophic factor

Term · Chemistry · MLC-T-CHM-002076

A protein belonging to the cytokine family that promotes the survival of neurons and oligodendrocytes. It signals through a receptor complex that includes the CNTF receptor alpha subunit and other components shared with leukemia inhibitory factor. Originally identified for its action on ciliary ganglion neurons, it also supports the differentiation of glial cells like astrocytes.

Table 1. Record
IdentifierMLC-T-CHM-002076
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 857 (https://doi.org/10.1515/pac-2015-0103)
See alsoAstrocyte; Nerve growth factor; Neurite; Neurotransmitter
Record as JSON
{
  "id": "MLC-T-CHM-002076",
  "term": "Ciliary neurotrophic factor",
  "field": "Chemistry",
  "definition": "A protein belonging to the cytokine family that promotes the survival of neurons and oligodendrocytes. It signals through a receptor complex that includes the CNTF receptor alpha subunit and other components shared with leukemia inhibitory factor. Originally identified for its action on ciliary ganglion neurons, it also supports the differentiation of glial cells like astrocytes.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "astrocyte",
    "nerve growth factor",
    "neurite",
    "neurotransmitter"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 857 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/ciliary-neurotrophic-factor/"
}

Record 2,224 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.