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Major histocompatibility complex class III molecule

Term · Chemistry · MLC-T-CHM-006931

A protein encoded by genes located within the major histocompatibility complex region, but structurally and functionally distinct from class I and class II molecules. These molecules do not present antigens but include components of the complement system, such as C2 and C4, and cytokines like tumor necrosis factor. Their genes are situated between the class I and class II gene regions on the chromosome.

Table 1. Record
IdentifierMLC-T-CHM-006931
FieldChemistry
SubjectChemistry and Human Health
Synonymsclass III MHC gene product; MHC class III molecule
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoMajor histocompatibility complex class II molecule; Lymphotoxin; Major histocompatibility complex; Major histocompatibility complex class I molecule; Tumor necrosis factor
Record as JSON
{
  "id": "MLC-T-CHM-006931",
  "term": "Major histocompatibility complex class III molecule",
  "field": "Chemistry",
  "definition": "A protein encoded by genes located within the major histocompatibility complex region, but structurally and functionally distinct from class I and class II molecules. These molecules do not present antigens but include components of the complement system, such as C2 and C4, and cytokines like tumor necrosis factor. Their genes are situated between the class I and class II gene regions on the chromosome.",
  "synonyms": [
    "class III MHC gene product",
    "MHC class III molecule"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "major histocompatibility complex class II molecule",
    "lymphotoxin",
    "major histocompatibility complex",
    "major histocompatibility complex class I molecule",
    "tumor necrosis factor"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/major-histocompatibility-complex-class-iii-molecule/"
}

Record 7,341 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.