Restriction fragment length polymorphism
Term · Chemistry · MLC-T-CHM-010277
A variation in the length of DNA fragments produced by digestion with a specific restriction endonuclease, due to differences in the DNA sequence at or between restriction sites. These polymorphisms are used as genetic markers for mapping and identifying individuals. The fragments are separated and visualized using gel electrophoresis.
| Identifier | MLC-T-CHM-010277 |
|---|---|
| Field | Chemistry |
| Subject | Analytical Chemistry |
| References | PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1152 (https://doi.org/10.1515/pac-2016-1120) |
Record as JSON
{
"id": "MLC-T-CHM-010277",
"term": "Restriction fragment length polymorphism",
"field": "Chemistry",
"definition": "A variation in the length of DNA fragments produced by digestion with a specific restriction endonuclease, due to differences in the DNA sequence at or between restriction sites. These polymorphisms are used as genetic markers for mapping and identifying individuals. The fragments are separated and visualized using gel electrophoresis.",
"subject": "Analytical Chemistry",
"references": [
"PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1152 (https://doi.org/10.1515/pac-2016-1120)"
],
"url": "https://mlchart.com/terminology/chemistry/restriction-fragment-length-polymorphism/"
}
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