Endonuclease

{
  "id": "MLC-T-CHM-013069",
  "term": "Endonuclease",
  "field": "Chemistry",
  "definition": "An enzyme that cleaves the phosphodiester bonds within a polynucleotide chain, such as DNA or RNA. Unlike exonucleases, which cut from the ends of a nucleic acid strand, endonucleases can cut at specific internal sites or non-specifically within the molecule. Restriction endonucleases, a specific class, recognize and cleave DNA at particular short nucleotide sequences, making them fundamental tools in molecular cloning and DNA mapping.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1146 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/endonuclease/"
}