Strand break

{
  "id": "MLC-T-CHM-011456",
  "term": "Strand break",
  "field": "Chemistry",
  "definition": "A disruption in the phosphodiester backbone of a nucleic acid molecule, such as DNA or RNA. This can occur as a single-strand break, affecting one of the two strands, or a double-strand break, affecting both strands simultaneously. Strand breaks are often induced by radiation or chemical agents and can have serious biological consequences.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1153 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/strand-break/"
}