anti-CD19/CD3 bispecific antibody CN201

{
  "id": "MLC-T-ONC-010276",
  "term": "anti-CD19/CD3 bispecific antibody CN201",
  "field": "Oncology and biomedicine",
  "definition": "A bispecific antibody and a T-cell engager targeting both the tumor-associated antigen (TAA) CD19, and the T-cell surface antigen CD3, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD19/CD3 bispecific antibody CN201 binds to both the CD3 antigen on T cells and the CD19 antigen expressed on tumor cells. This results in the cross-linking of T cells and tumor cells, and induces a cytotoxic T-lymphocyte (CTL) response against CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen overexpressed in B-cell lineage malignancies.",
  "synonyms": [
    "anti-CD19/anti-CD3 bispecific antibody CN201",
    "CD19 x CD3 bispecific antibody CN201"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-cd19-cd3-bispecific-antibody-cn201/"
}