anti-EGFR/anti-c-Met monoclonal antibody FPI-2053

{
  "id": "MLC-T-ONC-010601",
  "term": "anti-EGFR/anti-c-Met monoclonal antibody FPI-2053",
  "field": "Oncology and biomedicine",
  "definition": "A humanized bispecific monoclonal antibody targeting epidermal growth factor receptor (EGFR) and hepatocyte growth factor receptor (HGFR; c-Met), that can potentially be used as a ligand in radiotherapy. Upon administration, anti-EGFR/anti-c-Met monoclonal antibody FPI-2053 simultaneously targets and binds to the extracellular domains of both EGFR and c-Met expressed on cancer cells. EGFR and c-Met, both upregulated or mutated in a variety of tumor cell types, play key roles in tumor cell proliferation.",
  "synonyms": [
    "anti-EGFR x anti-c-Met monoclonal antibody FPI-2053",
    "anti-EGFR/anti-c-Met bispecific antibody FPI-2053",
    "anti-EGFR/c-Met antibody FPI-2053"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-egfr-anti-c-met-monoclonal-antibody-fpi-2053/"
}