anti-EGFR fluorescence imaging agent ABY-029

{
  "id": "MLC-T-ONC-010590",
  "term": "anti-EGFR fluorescence imaging agent ABY-029",
  "field": "Oncology and biomedicine",
  "definition": "A fluorescence imaging and contrast agent composed of an epidermal growth factor receptor (EGFR)-targeting affibody tracer molecule and labeled, through maleimide, with a near-infrared (NIR) fluorescent probe, IRDye 800CW, with potential use in the imaging of EGFR-overexpressing cells. Upon administration, ABY-029 targets and binds to EGFR-overexpressing tumor cells. Upon fluorescent imaging, the fluorescent dye can be visualized and EGFR-positive tumor cells can be detected.",
  "synonyms": [
    "ABY-029 trifluoroacetate salt",
    "IRDye 800CW maleimide-labeled affibody peptide",
    "fluorescently-labeled Anti-EGFR affibody molecule ABY-029"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/anti-egfr-fluorescence-imaging-agent-aby-029/"
}