aurora kinase inhibitor SNS-314

{
  "id": "MLC-T-ONC-011308",
  "term": "aurora kinase inhibitor SNS-314",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS-314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/aurora-kinase-inhibitor-sns-314/"
}