autologous dendritic cell-adenovirus p53 vaccine

{
  "id": "MLC-T-ONC-011601",
  "term": "autologous dendritic cell-adenovirus p53 vaccine",
  "field": "Oncology and biomedicine",
  "definition": "An autologous vaccine composed of dendritic cells (DC) that have been transduced with a p53 tumor suppressor gene-modified virus. When the autologous dendritic cell-adenovirus p53 vaccine is administered, the host cytotoxic T lymphocytes (CTL) are directed against p53-positive tumor cells, which may result in tumor cell death and decreased tumor growth.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-dendritic-cell-adenovirus-p53-vaccine/"
}