autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine

{
  "id": "MLC-T-ONC-011602",
  "term": "autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T-cell and antibody responses to melanoma cells bearing shared melanoma antigens such as MelanA/MART-1, gp100, MAGE3, resulting in tumor cell lysis.",
  "synonyms": [
    "Allogeneic Melanoma Cell-Loaded Dendritic Cell Vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-dendritic-cell-allogeneic-melanoma-tumor-cell-lysate-vaccine/"
}