MLchartDataset catalogue

flouride F 18 fluoropivalate

Term · Oncology and biomedicine · MLC-T-ONC-013624

A radioconjugate composed of fluoropivalate, a non-natural short-chain fatty acid (SCFA), labeled with the positron-emitting radioisotope fluorine F 18, with potential use as an imaging agent for tracing SCFA metabolism upon positron emitting tomography (PET)/computed tomography (CT). Upon administration, fluorine F 18 FPIA is rapidly taken up by tumor cells. This may allow for the visualization of tumor cells upon PET/CT. SCFA is used as an energy source for cell growth and proliferation; tumor cells take up SCFAs at a much higher rate than normal, healthy cells due to their increased energy demand to allow for rapid tumor cell proliferation.

Table 1. Record
IdentifierMLC-T-ONC-013624
FieldOncology and biomedicine
Synonyms18F-fluoropivalate; [18F]fluoro-2,2-dimethylpropionic acid; 3-18F-fluoro-2,2-dimethylpropionic acid; [18F]FPIA
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013624",
  "term": "flouride F 18 fluoropivalate",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of fluoropivalate, a non-natural short-chain fatty acid (SCFA), labeled with the positron-emitting radioisotope fluorine F 18, with potential use as an imaging agent for tracing SCFA metabolism upon positron emitting tomography (PET)/computed tomography (CT). Upon administration, fluorine F 18 FPIA is rapidly taken up by tumor cells. This may allow for the visualization of tumor cells upon PET/CT. SCFA is used as an energy source for cell growth and proliferation; tumor cells take up SCFAs at a much higher rate than normal, healthy cells due to their increased energy demand to allow for rapid tumor cell proliferation.",
  "synonyms": [
    "18F-fluoropivalate",
    "[18F]fluoro-2,2-dimethylpropionic acid",
    "3-18F-fluoro-2,2-dimethylpropionic acid",
    "[18F]FPIA"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/flouride-f-18-fluoropivalate/"
}

Record 7,354 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.