Fluorine F 18 3F-PHPG

{
  "id": "MLC-T-ONC-013657",
  "term": "Fluorine F 18 3F-PHPG",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate containing a substrate of the norepinephrine transporter (NET), chromaffin granule amine transporter (CGAT; vesicular monoamine transporter 1; VMAT1; VAT1; solute carrier family 18 member 1; SLC18A1) and synaptic vesicular amine transporter (SVAT; vesicular monoamine transporter 2; VMAT2; VAT2; solute carrier family 18 member 2; SLC18A2) labeled with the positron-emitting radioisotope fluorine F 18, with potential diagnostic imaging applications upon positron emitting tomography (PET)/computed tomography (CT). Upon administration, fluorine F 18 3F-PHPG is taken up by NET, VMAT1 and VMAT2 and accumulates in adrenergic tissues. This may allow for the visualization of tumors expressing these transporters upon PET/CT. NET, VMAT1 and/or VMAT2 are expressed in some adrenergic tumors.",
  "synonyms": [
    "[18F]3F-PHPG",
    "3-[18F]fluoro-para-hydroxyphenethylguanidine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-3f-phpg/"
}