fluorine F 18 dasatinib

{
  "id": "MLC-T-ONC-013667",
  "term": "fluorine F 18 dasatinib",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of a derivative of the multi-targeted kinase inhibitor dasatinib conjugated to the radioisotope fluorine F 18, with potential imaging activity during positron emission tomography (PET). Upon administration of fluorine F 18 dasatinib, dasatinib targets and binds to Bcr/Abl, SRC-family protein-tyrosine kinases, c-Kit and platelet-derived growth factor receptor (PDGFR). Upon binding, the fluorine F 18 moiety allows PET imaging of tumor cells and can be used as a tracer for the biodistribution of dasatinib.",
  "synonyms": [
    "[18F] SKI-249380",
    "F-SKI249380",
    "fluorine F 18 SKI-249380",
    "fluoro(F18)-dasatinib",
    "SKI-249380 F-18"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-dasatinib/"
}