Indium In 111-DOTA-biotin

{
  "id": "MLC-T-ONC-014429",
  "term": "Indium In 111-DOTA-biotin",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate of biotin conjugated with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and labeled with indium 111 (In-111). Biotin is a water-soluble B-complex vitamin, present in minute amounts in every living cell, while its level in cancerous tissue is higher than that of normal tissue. In 111-DOTA-Biotin could be used in 3-step pre-targeting radioimmunotherapy that employs tumor targeting antibody conjugated with streptavidin, the natural ligand of biotin.",
  "synonyms": [
    "In 111-DOTA-Biotin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/indium-in-111-dota-biotin/"
}